John O'Dea M.D.
"Now more than ever, the most important decision in a woman's life may well be whether or not to take hormone replacement at menopause. After fifteen years of mindless negativity based on publications generated from a single, deeply flawed, fundamentally invalid study, the treatment of menopause needs to be revolutionized. Finally we realize that sex hormones, far from just being sexual, have influences spreading far beyond the sexual domain, while operating not only over the long haul as was preciously thought, but from moment to vital moment. It follows that hormonal flux fuels a wide variety of health disturbances involving brain, mind & the immune/inflammatory system. This changes the ground rules for menopausal therapy & how it is delivered at a fundamental level, while invalidating previous menopausal studies. And it mandates the critical need for therapeutic precision, not only in terms of individualized dosages but their balances & even their patterns".