PrecisionHRT

PrecisionHRT

PrecisionHRT

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      • Categories
        • True Meaning of Menopause
        • Hormone fears and phobias
        • Menopausal Consequences
        • New vision of hormones
        • Traditional, Alternative or Precision?
        • Probably the best approach
        • Benefits of precision HRT
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        Safe, healthful HRT is now available

        The crucial key to modern, science-based treatment is tailored precision; precision in dosage, in pattern, in the balance between hormones & in the strict avoidance of oral hormones, particularly progestins.  Precision is key to HRT!

         

        A time for change; new paradigms in migraine

        Some twenty or so years go a concerted effort was made to improve the quality of women's medicine by increasing the proportion of women practicing medicine in the US, particularly within the field of women's healthcare, so as to presumably reduce sexism & gender bias. 

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  • Hormonal Articles
      • The True Meaning of Menopause
      • Hormone fears and phobias
      • Menopause and consequences
      • New vision of hormones
      • Benefits of precision HRT
      • Probably the best approach
      • Traditional, Alternative or Precision?
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Frequently asked questions

Why are the dynamic patterns just as important if not more so than their blends & balances, in HRT formulas?
Why is progesterone so heavily pushed & publicized in alternative circles when it & synthetic progestins rather than estrogens are the real promoters of breast cancer risk?
Why are oral forms of menopausal estrogen such as horse estrogens still in use?

If like me you reason that 'natural' is an adverb rather than an adjective, then you will agree that the best road toward natural hormone therapy must involve copying the ways of nature, not slavishly but by retaining its benefits while culling out what is unhealthful.  And there is nothing natural about oral hormone therapy, whether equine or otherwise.  'Natural' hormone therapy implies the use of estradiol, administered non-orally because oral estradiol has an unnatural up & down pattern, lasts far too briefly in the blood stream & is about 60% converted by the liver into estrone as it passes into the bloodstream.   And in the natural pre-menopausal woman, estradiol levels are quite stable, contrary to popular opinion.  It follows that HRT should be delivered in a steady, non-erratic flow, never dipping to zero. 

'Natural' hormones

Excessive dipping in the estradiol level carries its own group of special risks & side-effects such as increased inflammation, migraines & breast cancer risk & should be assiduously avoided, hence the need for a steady-state delivery.  So natural estrogen therapy involves the use of non-oral estradiol, delivered in a steady, non-dipping fashion, adjusted to a dosage that accommodates the individual woman's personal rate of estrogen excretion, whether fast or slow. 

Can judicious hormone therapy fix sexual dysfunction & loss of desire around menopause?

A: indeed it can, by its antidepressant effects,(depression destroys sexuality), by reducing the need for antidepressant drugs which also hinder sexual desire & function, & by direct stimulatory effects on the brain centers that drive sexuality.  That's a three pronged benefit!

Why do insurance companies and the medicare system reject hormone therapy on the basis of a single, badly flawed study using oral horse estrogens & an atypical, excessively potent synthetic progestin?
Why do the precise blends & balances of hormones matter just as much as the hormones themselves?
Are the powers that be right or wrong when they pan hormone therapy of the menopause?
About 2 years before my periods ended I began to experience difficulty with concentration, memory and intellectual function. Am I heading for Alzheimer's disease?

A: Many women experience cognitive dysfunction or mind fog around the time of menopause that has nothing to do with real dementia, which should of course be tested for if the problem persists. This is what I call menopausal pseudo-dementia and it can rapidly be corrected with precision hormone therapy whereas psychoactive drugs (which the government recommends in lieu of hormones at menopause) can make brain-fog even worse and tend to increase stroke risk, the very complication the federales have used to condemn HRT in women over 60, as it turns out, quite erroneously.

Can hormone therapy reduce Alzheimer's disease risk, even reverse it?
What can be done about bone loss that's already accrued from osteoporosis?

A.Studies on estrogen therapy for bone loss reversal have not been impressive, probably because these studies used oral equine estrogens and at lower than effective doses. Oral estrogens have My health food store says Calcium supplements are a good treatment for osteoporosis prevention & even reversal, & they sell me a special, super-expensive chelated kind. Is this valid?

A: Calcium supplements, in the absence of hormone therapy offer no benefits for osteoporosis prevention or reversal in menopausal women. On the other hand evidence seems to suggest that menopausal Calcium supplementation may increase heart disease risk & cardiac events in menopausal women. I do not recommend Calcium supplements but vitamin D needs supplementing in many women.

So what's the problem in the woman with a uterus? If she takes progesterone along with her estrogen, uterine cancer is prevented, right?

A. Yes, cancer risk is reduced compared with women taking no hormones, but progesterone & synthetic progestins are the principle cause of side-effects such as fatigue, brain fog & depression that some women experience with menopausal HRT, and they also increase the risk for breast cancer, a very big deal. However the expert physician can get around this problem by employing special progestins and special ways of giving them so as to retain the benefits while avoiding the pitfalls. That is why one needs an expert and individualized instead of standardized care.

Are hormone-related endometrial hyperplasia & cancer as serious as non hormone-related endometrial cancer?

No, HRT-related "cancer" looks like cancer under the microscope but doesn't behave like it. It is preceded by a process called 'endometrial hyperplasia', a microscopic thickening of the endometrium or inner lining of the womb. A treatment with progestin or a D and C will usually take care of it. If you look at women who take estrogen along with progestin, they actually have a lower cancer risk in this tissue than those taking no hormones at all.

What makes "bio-identical hormone therapy" different from the modern, high quality, precisely-dosed estradiol patches and pellets of big pharma?
I'm about 4 years into menopause & I still have my womb. What about hormones & uterine cancer?

The uterus is like an inverted flask or bottle & it has 2 tissues, the endometrium in the body of the uterus and the cervix near the bottle-neck, just above the vagina. Cancer of the cervix is related to infection with papilloma virus and is diagnosed by PAP smears. Endometrial cancer is of 2 types, that associated with HRT & that unrelated to HRT. The kind unrelated to HRT can progress to cause serious health problems, & is commoner in obese women. In contrast the kind seen in association with hormone therapy only occurs when estrogen is given without progesterone. This condition is in a sense a cosmetic cancer and is non-progressive. Women taking estrogen plus progesterone in combination have a lower uterine cancer risk than women taking no hormones at all. The trick here is finding a progestin or progesterone delivery system that retains this anti-cancerous quality at the womb without also receiving the negative consequences of progestin therapy, and this can easily be accomplished.

My friends tell me I'm crazy to take hormones because they cause cancer. Do you agree?

That's pretty vague, isn't it? What kind of cancers, prostate cancer? You don't have one. "What about colon cancer ", you ask? Actually estradiol reduces colon cancer risk! Surely breast cancer then? There is no evidence that estrogen therapy, even when using antiquated oral equine products, increases breast cancer risk, in fact it may reduce it. There is a fundamental difference between considering factors that cause cancer or trigger cancer, & factors that aggravate an already existing cancer. That being said, a flare-up in a hidden, unsuspected breast cancer may bring it to your attention sooner rather than later, facilitating early, preemptive treatment.

Have you had personal experience with salivary hormone results?

<p>Indeed I have, in patients who had also attended other health providers &amp; some of these results were clearly absurd, such as the high progesterone levels reported in a 68 years old female patient who wasn't taking any progesterone whatever. This was either a miracle or a ludicrous result, perhaps even a scam.</p>

My family doctor checks me by measuring the estrogen levels in my saliva & says these test allow him to individualize my care. Can this be true ?

Absolutely not, unless your objective is to alter your saliva. Beyond trusting hormone measurements in the saliva offered by unaccredited labs, even blood levels of estradiol & testosterone from accredited, government-monitored laboratories are of limited use for monitoring hormone therapy. If those big labs believed they could credibly measure salivary sex hormone levels on a commercial basis, you can be sure they would do so, but they do not. And in my own experience the results from some of these other, non-accredited labs are often ridiculously misleading and glaringly inaccurate.

Why do women erroneously believe that estrogen increases breast cancer?

A. The media & even professionals often believe estrogen increases breast cancer risk.  This is definitively untrue.  What is true is that estrogen therapy given to a woman who already has a breast cancer can trigger a flare up, although this may be good since an earlier cancer diagnosis may ensue.  The estrogens stimulate two kinds of receptors, alphas and betas. Activated beta receptors actually reduce breast cancer risk. Genistien is a selective stimulator of beta estrogen receptors and testosterone therapy at menopause indirectly increases beta receptor stimulation.  Perhaps that is why I have seen only a tiny number of breast cancers during my years in practice, TG. 

My nurse practitioner says she's a female hormone expert because she is a woman & has had special training in naturopathy. Can this be true?

No, naturopathy is neither a valid medical specialty nor a substitute for formal training in gynecology, endocrinology or internal medicine. Far worse than being ignorant is the unawareness of one's profound ignorance.

Why is precision a critical factor for administering safe & effective sex hormone therapy?
Is "anti-aging medicine" for real?

A: If you mean growth hormone therapy, no. There is a group of practitioners, many of them without endocrine training or expertise who tout injections of human growth hormone (hGH) as an extremely expensive anti-aging remedy, along with their own nutritional supplements. Unvalidated oral products are also sold that supposedly instruct the body to produce more hGH by itself. The testing hGH doctors base their treatments on does not necessarily validate growth hormone deficiency. Many of those who experience improvements in energy & vigor do so because the hGH shots stimulate the body to make more testosterone, a hormone that generates increased vigor & energy, which may alone be deficient in the group of patients that seek these doctors out, people for instance with chronic fatigue & depression. But hGH promotes diabetes risk & kidney disease. It also synergizes with testosterone to promote prostate cancer in men and masculinization in women. If one felt better when taking hGH it would be far less expensive to see if your testosterone level was low & then supplement it carefully & directly, instead of playing this hGH game based on intellectual dishonesty.

I’m only 35 but I’ve already had a hysterectomy. Do I need hormones?

A. Hormone therapy is needed only if they also removed your ovaries, although during some hysterectomies the blood supply to the ovaries becomes unintentionally compromised leading to early ovarian failure,& since the uterus & the menstrual cycle, an accurate marker for ovarian function are no longer present, the victim can no longer make a connection between menstrual cycle patterns and early symptoms of premature menopause, such as mood & personality changes along with insomnia, and by default they often go the psychiatric route instead.

Your Medical Visit

Your first visit.

This visit is straightforward. Through history & physical we painstakingly assemble your story. You are in the driver’s seat & you always know & understand what’s going on.

Our method.

We don’t treat mental illness, forcefully with mind-invading drugs that alter who you are. We treat people, using a medical instead of a psychiatric model of care, seeking to make your psychiatrist’s & psychologist’s lives easier as we strive to ease your pain.

Our role.

Our role is neither to force treatments upon you or to one up your psychiatrist. It is to naturally, permissively reduce you mind-based disturbances in a natural manner instead of painting a forceful smile on your face, at the cost of true happiness & life’s enjoyment.

A beautiful mind.

A normal mind is our most precious possession. It isn’t our purpose to just shut you up so that you stop bothering others; we want to restore your normal mind.

Your Medical Consultation

Your medical consultation

The following steps are intended to take you through your unique, personalized medical experience, from initial visit through diagnosis & treatment to ultimate projected treatment outcome. 

Initial visit, assessment, plan & actualization

The purpose of this visit is for us to get to know each other, since it is a two-way street where feedback can be critical & your voice really matters.  You meet the doctor in his pleasant office overlooking the Pacific ocean & spend about an hour and a half unhurriedly putting your data together as they pertain to menopause. Then, on the basis of ah experienced, insightful medical assessment he assembles a detailed picture, from history, physical, old records or new blood tests of what the menopause is really doing to you in terms of your particular case & how best to deal with the situation with sophisticated precision, involving a rational treatment protocol.

 

Follow up visits

Treating the mechanisms of disease instead of meaningless labels

Once your situation has been defined, not in the crude terms of whether or not you have gone through the menopause, but rather in the exquisitely precise terms of which hormones have become depleted, excessive, unopposed or highly erratic, then we can treat these individual hormonal disease-promoting mechanisms rather than such meaningless labels as pre-menopause, menopause or peri-menopause. In other words our treatment targets are the processes that underlie medical risk rather than the superficial labels that have been arbitrarily pasted over our problems ms superficially.  

The early days

Fine-tuning your prescription

Medical doctors are not psychics.  They are not equipped to look at you while holding a crystal ball & tell you exactly what dosages & levels of hormones will suit your particular purpose.  After all, some women excrete estrogen at rates twice as fast as others, so a one size fits all approach makes no sense.  The early days of menopause therapy require some give and take, some interplay between doctor & patient while the correct dosages & hormone patterns are established, but once the dust has settled you should expect both short & long term successes, on terms of how you feel, your body weight, sexual function, physical appearance & whether you can undergo a reduction in other medications such as anti-depressants, sedatives, pain pills, headache pills & so forth. 

Long term goals

Benefits of long-term hormone therapy

Unless their is a specific reason to quit, HRT should be continued for the rest of your life, as long as it is non-oral & involves estradiol plus/minus testosterone, in natural female-appropriate dosages.  Blanket advisements to quit sooner or soonest are stupid, IMO. Long term benefits of precision forms of HRT include prevention of heart disease, stroke & dementia, prevention or reversal of osteoporosis, sexual restoration, anti-aging cosmetic effects, a longer lifespan, & prevention of breast & colon cancer, but remember this; age is the b greatest risk factor for cancer.  That;s why I coined my own, personal Yogi Berra-ism: "If you live long enough, your gonna die."

 

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